evaluation of first voided urine samples for detection of ureaplasma uriealyticum and mycoplasma hominis in urinary tracts of men and women suffering from nongonococcal and nonspecific urethritis

introduction: ureaplasma uriealyticum is one of the most important causes of nongonococcal and nonspecific urethritis (ngu & nsu) in men. mycoplasma hominis too has a causal role in ngu & nsu. this study aimed to investigate whether it is possible to detect mycoplasma hominis and ureaplasma uriealyticum in first voided urine samples in men suffering from ngu & nsu without complaints of urethral secretions and in women with clinical symptoms despite negative vaginal secretion culture test results. methods: first voided urine samples were taken from 150 patients (21 women & 129 men) suffering from ngu & nsu who referred to the division of bacteriology, school of public health, tehran university of medical sciences in 2004-2005. samples were examined by culture method. results: cultures were positive for mycoplasma and ureoplasma in 49 (32.6 %) of the 150 samples. of the 21 samples taken from women, 5 samples were positive for mycoplasma & ureoplasma (2 samples mycoplasma, 3 samples ureaplasma). samples from 44 men were positive for ureoplasma & mycoplasma(17 samples mycoplasma, 4 samples ureaplasma and 23 samples were positive for both). ureoplasma urealyticum was detected in 30 samples (20%) and mycoplasma hominis, was detected in 42 samples (28%). conclusion: the results of this study provides evidence that culture tests can be done using voided urine in order to detect mycoplasma hominis and ureaplasma urealyticum in patients suffering from nongonococcal urethris men who do not have urethral secretions and women with clinical symptoms despite negative vaginal secretion culture test results.